180 patients comparing different booster agents
As part of the CAREforCOLON program, a GCP-compliant trial with 180 patients was conducted to assess the performance of different booster agents.
Besides cleansing the bowel comprehensively, the second key success criterium for a complete colon capsule endoscopy is capsule excretion. To facilitate movement of the capsule through the bowel at a speed that is neither too fast (to miss key findings) nor too slow (to have the battery run out before reaching the anal valve), a booster agent is applied to stimulate motility. To compare different agents, this trial split the patients into three cohorts that were all provided with a colon capsule endoscopy by CHI, but with different regimens of medication to take after swallowing the capsule.
Like all the other CAREforCOLON program trials, this was led by Odense University Hospital in collaboration with Medtronic and sundhed.dk, CorporateHealth provided patient management and video analysis.